Comparison of gentamicin distribution in the inner ear following administration via the endolymphatic sac or round window.

Abstract

OBJECTIVE/HYPOTHESIS The distribution of gentamicin in the inner ear via the endolymphatic sac (ES) or round window (RW) routes was investigated. STUDY DESIGN Experimental study. METHODS A fluorescent gentamicin-Texas Red conjugate (GTTR) was adopted to visualize the gentamicin. Adult guinea pigs were treated with GTTR applied to the ES or RW, the… (More)
DOI: 10.1002/lary.21041

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