Comparison of fresh and cultured islets from human and porcine pancreata.

  title={Comparison of fresh and cultured islets from human and porcine pancreata.},
  author={Hirofumi Noguchi and Bashoo Naziruddin and M Shimoda and Yasutaka Fujita and Daisuke Chujo and Morihito Takita and H Peng and Koji Sugimoto and T Itoh and Yoshiko Tamura and Greg S Olsen and Naoya Kobayashi and Nicholas Onaca and Marlon F. Levy and Shinichi Matsumoto},
  journal={Transplantation proceedings},
  volume={42 6},
INTRODUCTION For clinical islet transplantation, many centers have recently introduced of human islet cultures prior to transplantation. They provide flexibility to evaluate isolated islets and pretreat patients. However, isolated islets deteriorate rapidly in culture. In the present study, we compared fresh human and porcine islets with cultured islets for c-Jun NH(2)-terminal kinase (JNK) activity. MATERIALS AND METHODS Islet isolations from human and porcine pancreata were performed using… CONTINUE READING