Comparison of free and total forms of serum human kallikrein 2 and prostate-specific antigen for prediction of locally advanced and recurrent prostate cancer.

@article{Steuber2007ComparisonOF,
  title={Comparison of free and total forms of serum human kallikrein 2 and prostate-specific antigen for prediction of locally advanced and recurrent prostate cancer.},
  author={Thomas Steuber and Andrew J. Vickers and Angel M Serio and Ville Vaisanen and Alexander Haese and Kim Pettersson and James Andrew Eastham and Peter T. Scardino and Hartwig Huland and Hans G Lilja},
  journal={Clinical chemistry},
  year={2007},
  volume={53 2},
  pages={233-40}
}
BACKGROUND We evaluated the association of total and free forms of serum human kallikrein 2 (hK2) and prostate-specific antigen (PSA) with prostate cancers of unfavorable prognosis. METHODS We retrospectively measured total PSA (tPSA), free PSA (fPSA), and total hK2 (thK2) in preoperative serum samples from 867 men [and assessed free hK2 (fhK2) measured in 577 of these men] treated with radical prostatectomy for clinically localized prostate cancer. Associations between biomarker… CONTINUE READING