Comparison of flutamide and Emcyt in hormone-refractory metastatic prostatic cancer.

@article{Kernion1988ComparisonOF,
  title={Comparison of flutamide and Emcyt in hormone-refractory metastatic prostatic cancer.},
  author={J N de Kernion and Gerald P. Murphy and Roger L. Priore},
  journal={Urology},
  year={1988},
  volume={31 4},
  pages={312-7}
}
A prospective randomized trial for metastatic prostatic cancer in 220 patients who were refractory to hormone therapy was conducted by the National Prostatic Cancer Project from 1984 to 1985. As of July, 1986, the evaluation of these patients reflected no difference in response to either estramustine phosphate (Emcyt) or flutamide. Toxicities were minimal, and the observed survival and progression-free survival intervals were noteworthy in view of the overall prospects for such patients. Future… CONTINUE READING