Comparison of escitalopram vs. citalopram and venlafaxine in the treatment of major depression in Spain: clinical and economic consequences

@article{SicrasMainar2010ComparisonOE,
  title={Comparison of escitalopram vs. citalopram and venlafaxine in the treatment of major depression in Spain: clinical and economic consequences},
  author={Antoni Sicras-Mainar and Ruth Navarro-Artieda and M. Blanca-tamayo and Victoria Gimeno-de la Fuente and Jordi Salvatella-Pasant},
  journal={Current Medical Research and Opinion},
  year={2010},
  volume={26},
  pages={2757 - 2764}
}
Abstract Study objective: Population based study to determine the clinical consequences and economic impact of using escitalopram (ESC) vs. citalopram (CIT) and venlafaxine (VEN) in patients who initiate treatment for a new episode of major depression (MD) in real life conditions of outpatient practice. Methods: Observational, multicenter, retrospective study conducted using computerized medical records (administrative databases) of patients treated in six primary care centers and two hospitals… Expand
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References

SHOWING 1-10 OF 38 REFERENCES
Comparison of escitalopram versus citalopram for the treatment of major depressive disorder in a geriatric population.
TLDR
Geriatric patients treated with escitalopram had better treatment persistence, fewer hospitalizations, and lower medical and total healthcare costs than patientstreated with citaloprams. Expand
Cost-effectiveness of escitalopram vs. citalopram in major depressive disorder
TLDR
It is demonstrated that escitalopram is a cost-effective first-line treatment option for major depressive disorder and is associated with lower healthcare costs. Expand
Healthcare expenditure in severely depressed patients treated with escitalopram, generic SSRIs or venlafaxine in the UK
TLDR
The results of this real-life study bring additional evidence of escitalopram appearing to be a cost-effective treatment for patients suffering from severe depression as diagnosed in routine practice and could be considered for first-line treatment in these patients. Expand
Comorbilidad y coste ambulatorio asociado a los pacientes con trastornos depresivos en un ámbito poblacional
TLDR
Prevalence of DD was higher, particularly in women, and following adjustment in accordance with comorbidity, age and sex, DD outpatients used more health care resources and implied higher costs. Expand
Escitalopram versus other antidepressive agents for depression.
TLDR
Some statistically significant differences favouring escITALopram over other antidepressive agents for the acute phase treatment of major depression were found, in terms of efficacy (citalopram and fluoxetine) and acceptability (duloxettine). Expand
Prospective, multicentre, randomized, double-blind study of the efficacy of escitalopram versus citalopram in outpatient treatment of major depressive disorder
TLDR
A double-blind, randomized clinical trial was performed in which general practitioners and psychiatrists compared fixed doses of escitalopram with citaloprams over 8 weeks in outpatients with major depressive disorder (MDD) and confirmed that escITALopram has a superior effect in MDD. Expand
Pharmacy and medical costs associated with switching between venlafaxine and SSRI antidepressant therapy for the treatment of major depressive disorder.
TLDR
Patterns of antidepressant drug use and depression-related and all-cause medical costs for patients who switched therapy between 2 drug classes, selective serotonin reuptake inhibitors (SSRIs) and the selective norepinephrine reptake inhibitor (SNRI) venlafaxine are explored. Expand
The effect of venlafaxine compared with other antidepressants and placebo in the treatment of major depression
TLDR
Venlafaxine appears more effective than SSRIs, and at least as effective as tricyclic antidepressants, in the treatment of major depressive episode. Expand
Clinical validity of a population database definition of remission in patients with major depression
TLDR
Results show an acceptable level of concordance between remission obtained from the computerized databases and clinical criteria, and the major discrepancies were found in diagnostic accuracy. Expand
[Prevalence of mental disorders and associated factors: results from the ESEMeD-Spain study].
TLDR
The ESEMeD-Spain study can provide careful outcomes to understand the impact of mental disorders in Spain; the influence of sociodemographic factors on its presence and age of onset of the disorders. Expand
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