Comparison of equipressor doses of norepinephrine, epinephrine, and phenylephrine on septic myocardial dysfunction.

@article{Ducrocq2012ComparisonOE,
  title={Comparison of equipressor doses of norepinephrine, epinephrine, and phenylephrine on septic myocardial dysfunction.},
  author={Nicolas Ducrocq and Antoine Kimmoun and Anna Furmaniuk and Zerin Hekalo and Fatiha Maskali and Sylvain Poussier and Pierre-Yves Marie and Bruno L{\'e}vy},
  journal={Anesthesiology},
  year={2012},
  volume={116 5},
  pages={
          1083-91
        }
}
BACKGROUND Myocardial depression is a frequent event during septic shock and may mimic a cardiogenic shock state with decreased cardiac output. Nevertheless, data are scarce regarding the myocardial effects of vasopressors used to treat hypotension. In this study, the authors compared the effects of three commonly used vasopressors acting on different adrenergic receptors on myocardial function in a rodent model of septic shock, as explored with conductance catheter and positron emission… CONTINUE READING
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