Comparison of environmental scanning electron microscopy with high vacuum scanning electron microscopy as applied to the assessment of cell morphology.

@article{McKinlay2004ComparisonOE,
  title={Comparison of environmental scanning electron microscopy with high vacuum scanning electron microscopy as applied to the assessment of cell morphology.},
  author={Karen J McKinlay and Francis J Allison and Colin A. Scotchford and David E. Grant and James M. Oliver and John R. King and John Wood and Paul D. Brown},
  journal={Journal of biomedical materials research. Part A},
  year={2004},
  volume={69 2},
  pages={359-66}
}
The efficacy of conventional high vacuum scanning electron microscopy (SEM), environmental SEM (ESEM), and confocal laser scanning microscopy techniques in the assessment of cell-material interactions is compared. Specific attention is given to the application of these techniques in the assessment of the early morphological response of human osteoblast-like cells cultured on titanium dioxide. The processing of cells cultured for conventional high vacuum SEM leads to the loss of morphological… CONTINUE READING

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