Comparison of energy components of proteins from thermophilic and mesophilic organisms

Abstract

In order to infer the energetic determinants of thermophilic proteins, molecular mechanics calculations were applied to five proteins from thermophilic eubacteria and their mesophilic homologs. The energy function includes a hydration term as well as theelectrostatic contribution from the solvent in addition to the usual conformational energy terms. We… (More)
DOI: 10.1007/s002490100161

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