Comparison of eltanolone and propofol on a pressure-volume analysis of the heart.

@article{Mulier1996ComparisonOE,
  title={Comparison of eltanolone and propofol on a pressure-volume analysis of the heart.},
  author={Jan Paul J. Mulier and h c Hugo Van Aken},
  journal={Anesthesia and analgesia},
  year={1996},
  volume={83 2},
  pages={233-7}
}
We designed a randomized study to compare the effect of eltanolone and propofol on cardiac contractility. Patients were anesthetized, tracheally intubated and ventilation controlled. Propofol, 1.25 or 2.5 mg/kg, or eltanolone, 0.5 or 1 mg/kg, or a lipid emulsion only was administered in an intravenous (i.v.) bolus dose. Pressure-volume analysis was used based on radial artery pressure and transesophageal left ventricular cross-sectional area. Both propofol and eltanolone have negative inotropic… CONTINUE READING