Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey

@article{Imbert2000ComparisonOE,
  title={Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey},
  author={Christelle Imbert and Erwan B{\'e}zard and St{\'e}phane Guitraud and Thomas Boraud and Christian Eric Gross},
  journal={Journal of Neuroscience Methods},
  year={2000},
  volume={96},
  pages={71-76}
}
The most valuable model of Parkinson's disease available at present is the primate model treated with 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP), frequently used to study response to new drugs or surgical treatments. The evaluation of such therapies requires clinical rating scales which measure precisely motor behaviour in both normal and parkinsonian monkeys. It is obvious that such evaluation can only be valid if parallel studies are carried out under similar experimental conditions… CONTINUE READING
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