Comparison of efficacy and safety of ciprofloxacin otic solution 0.2% versus polymyxin B-neomycin-hydrocortisone in the treatment of acute diffuse otitis externa*.

@article{Drehobl2008ComparisonOE,
  title={Comparison of efficacy and safety of ciprofloxacin otic solution 0.2% versus polymyxin B-neomycin-hydrocortisone in the treatment of acute diffuse otitis externa*.},
  author={Margaret A Drehobl and Juan Lorente Guerrero and Pilar Rivas Lacarte and Gary Goldstein and Francisco Mata and Stephen Luber},
  journal={Current medical research and opinion},
  year={2008},
  volume={24 12},
  pages={3531-42}
}
OBJECTIVE To compare the efficacy and safety of ciprofloxacin otic solution 0.2% to polymyxin B-neomycin-hydrocortisone (PNH) otic solution in the treatment of acute diffuse otitis externa in children, adolescents, and adults. METHODS This was a randomized, parallel-group, evaluator-blind, active-controlled, multicenter, noninferiority study. The primary efficacy endpoint was clinical cure of otitis symptoms at the test-of-cure (TOC) visit. Clinical cure at the end-of-treatment (EOT) visit… CONTINUE READING
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