Comparison of effects of enalapril plus hydrochlorothiazide versus standard triple therapy on renal function in renovascular hypertension.

@article{Franklin1985ComparisonOE,
  title={Comparison of effects of enalapril plus hydrochlorothiazide versus standard triple therapy on renal function in renovascular hypertension.},
  author={Stanley S. Franklin and R. D. Smith},
  journal={The American journal of medicine},
  year={1985},
  volume={79 3C},
  pages={
          14-23
        }
}
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A comparison of enalapril plus hydrochlorothiazide with standard triple therapy in renovascular hypertension.
TLDR
The self-limited increase in serum creatinine seen in 20% of renovascular hypertensive patients receiving enalapril and hydrochlorothiazide may identify a subset of patients with unilateral or bilateral high grade renal artery stenosis who should be treated with angioplasty or operative intervention.
Renal revascularization in the azotemic hypertensive patient resistant to therapy.
TLDR
Two studies indicate that refractory hypertension in association with renal insufficiency is a relatively common clinical presentation for renovascular hypertension and bilateral renal-artery disease and diagnostic evaluation and consideration of renal revascularization appear warranted in such patients.
Captopril versus enalapril maleate: a comparison of antihypertensive and hormonal effects.
TLDR
There is an acute depressor response with converting enzyme inhibition which is more pronounced with captopril than with enalapril and which correlates with an increase in plasma renin activity.
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Serial renal function studies were performed on 41 patients wtih renovascular hypertension (RVH) secondary to atherosclerotic renal artery disease who had been randomly selected for nonoperative management who had deterioration of renal function or loss of renal size that led to operation.
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TLDR
Investigation of the renal effects of the new angiotensin converting enzyme inhibitor enalapril and of its active metabolite MK-422 in patients with essential hypertension found either no, or even beneficial, effects on renal function.
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In 36 patients with normal renal function receiving hydrochlorothiazide and propranolol, lying diastolic blood pressure remained above 95 mmHg. In a double-blind trial, Step 3 therapy with 5–40
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