Comparison of double- and single-dose methotrexate protocols for treatment of ectopic pregnancy.

@article{Hamed2012ComparisonOD,
  title={Comparison of double- and single-dose methotrexate protocols for treatment of ectopic pregnancy.},
  author={Hossam O. Hamed and Salah Roshdy Ahmed and Abdullah Ali Alghasham},
  journal={International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics},
  year={2012},
  volume={116 1},
  pages={67-71}
}
OBJECTIVE To compare efficacy between double-dose methotrexate and single-dose methotrexate for treatment of tubal ectopic pregnancy (EP). METHODS Between March 2008 and February 2011,157 patients who had tubal EP diagnosed by a non-laparoscopic approach and were hemodynamically stable were enrolled in a prospective study in Qassim, Saudi Arabia. The participants were randomized to receive either double-dose (50mg/m(2) intramuscularly on days 0 and 4; group 1) or single-dose (50mg/m(2… CONTINUE READING

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