Comparison of distribution and photodynamic effects of di- and tetra-sulphonated aluminium phthalocyanines in normal rat colon.

@article{Chatlani1991ComparisonOD,
  title={Comparison of distribution and photodynamic effects of di- and tetra-sulphonated aluminium phthalocyanines in normal rat colon.},
  author={P. T. Chatlani and Joshua Bedwell and Alexander J. Macrobert and Hugh Barr and Paul B. Boulos and Neville Krasner and D. Phillips and Stephen G. Bown},
  journal={Photochemistry and photobiology},
  year={1991},
  volume={53 6},
  pages={745-51}
}
We have previously reported photodynamic therapy of normal rat colon using aluminium sulphonated phthalocyanine (AISPc). In that study, the AISPc used was a mixture of phthalocyanines of different degrees of sulphonation. Phthalocyanines of defined degrees of sulphonation have recently become available and we compared the distribution of the di- and tetra-sulphonates (AIS2Pc and AIS4Pc) in rat colon and colon wall structures employing both chemical extraction and fluorescence photometry using a… CONTINUE READING