Comparison of diltiazem and nifedipine alone and in combination in patients with coronary artery spasm.

@article{Prida1987ComparisonOD,
  title={Comparison of diltiazem and nifedipine alone and in combination in patients with coronary artery spasm.},
  author={Xavier E. Prida and John S. Gelman and Robert L. Feldman and James A. Hill and Carl J Pepine and Eric Scott},
  journal={Journal of the American College of Cardiology},
  year={1987},
  volume={9 2},
  pages={412-9}
}
Fifteen patients with coronary artery spasm completed a double-blind placebo-controlled trial comparing diltiazem and nifedipine. Increasingly, higher daily doses (diltiazem, 90 to 360 mg; nifedipine, 30 to 120 mg) were administered to achieve optimal clinical effects. Daily diaries and ambulatory electrocardiographic recordings were used to assess efficacy and side effects. Both drugs significantly decreased angina frequency compared with that in the preceding placebo period (diltiazem 1.4… CONTINUE READING

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