Comparison of different strategies to select aptamers against a transmembrane protein target.

Abstract

Binding of aptamers is dependent on their target conformation, which in turn is conditioned by the target's environment. Therefore, selection of aptamers against the active forms of membrane proteins could require their correct membrane insertion in order to maintain their native conformation. Here, we compare different SELEX strategies to identify aptamers… (More)

Topics

Cite this paper

@article{Pestourie2006ComparisonOD, title={Comparison of different strategies to select aptamers against a transmembrane protein target.}, author={Carine Pestourie and Laura Cerchia and Karine Gombert and Youssef Aissouni and Jocelyne Boulay and Vittorio de Franciscis and Domenico Libri and Bertrand Tavitian and Frederic Duconge}, journal={Oligonucleotides}, year={2006}, volume={16 4}, pages={323-35} }