Comparison of different protein concentration techniques within preformulation development.

Abstract

Highly concentrated antibody solutions are of increasing importance in the pharmaceutical industry. During production highly concentrated solutions are usually prepared by tangential flow filtration (TFF). Since this technique is often not applicable in the early phase of formulation development, where the available amounts of protein are commonly very… (More)
DOI: 10.1016/j.ijpharm.2011.09.028

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