Comparison of different methods for detecting epidermal growth factor receptor mutations in peripheral blood and tumor tissue of non-small cell lung cancer as a predictor of response to gefitinib

@inproceedings{Xu2012ComparisonOD,
  title={Comparison of different methods for detecting epidermal growth factor receptor mutations in peripheral blood and tumor tissue of non-small cell lung cancer as a predictor of response to gefitinib},
  author={Fei Xu and Jingxun Wu and Cong Xue and Yuanyuan Zhao and Wei Jiang and Liping Lin and Xuan Wu and Yachao Lu and Hua Bai and Jiasen Xu and Guanshan Zhu and Li Zhang},
  booktitle={OncoTargets and therapy},
  year={2012}
}
BACKGROUND Previous studies have reported that epidermal growth factor receptor (EGFR) mutation in tumor tissue and peripheral blood can predict the response to EGFR tyrosine kinase inhibitor (TKI) in non-small cell lung cancer (NSCLC). However, the heterogeneity of the sample sources makes it difficult to evaluate the detecting methodologies. The goal of this study is to compare different methods for analyzing EGFR mutation in blood and tumor tissue. MATERIALS AND METHODS Fifty-one advanced… CONTINUE READING

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