Comparison of different hepatocyte cell lines for use in a hybrid artificial liver model

@article{Takagi1997ComparisonOD,
  title={Comparison of different hepatocyte cell lines for use in a hybrid artificial liver model},
  author={Mutsumi Takagi and Noriko Fukuda and Touho Yoshida},
  journal={Cytotechnology},
  year={1997},
  volume={24},
  pages={39-45}
}
Selection of a cell line suitable for a hybrid artificial liver model employing cellulose porous beads (CPBs) was investigated. Hep G2 cells grown in a culture dish exhibited appreciably higher ureogenesis and gluconeogenesis activities than those grown in CPBs. SEM observation of CPBs revealed marked difference in the distribution of attached cells from one bead to another, and showed that almost all the cell-bearing micropores were completely packed with cells. With the aim of selecting a… CONTINUE READING