Comparison of different classes of radionuclides for potential use in radioimmunotherapy.


Currently, beta-emitting radionuclides are used almost exclusively in the clinic and in clinical radioimmunotherapy studies. The main advantage of beta-emitters is the relatively long path length in biological tissue (in the mm range), which is sufficient to irradiate cancer cells that do not have bound radiolabelled antibody (cross-fire effect). This… (More)


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