Comparison of cytomegalovirus (CMV) enzyme-linked immunosorbent spot and CMV quantiferon gamma interferon-releasing assays in assessing risk of CMV infection in kidney transplant recipients.

@article{Abate2013ComparisonOC,
  title={Comparison of cytomegalovirus (CMV) enzyme-linked immunosorbent spot and CMV quantiferon gamma interferon-releasing assays in assessing risk of CMV infection in kidney transplant recipients.},
  author={Davide A. Abate and Alda Saldan and Carlo Mengoli and Marta Fiscon and Cristina Silvestre and Loredana Fallico and Marta Peracchi and Lucrezia Furian and Riccardo Cusinato and Luciana Bonfante and Barbara Rossi and Francesco Marchini and Dino Sgarabotto and Paolo Rigotti and Giorgio Pal{\`u}},
  journal={Journal of clinical microbiology},
  year={2013},
  volume={51 8},
  pages={2501-7}
}
Assessing cytomegalovirus (CMV)-specific cell-mediated immunity (CMI) represents an appealing strategy for identifying transplant recipients at risk of infection. In this study, we compared two gamma interferon-releasing assays (IGRAs), Quantiferon-CMV and CMV enzyme-linked immunosorbent spot (ELISPOT), to determine the ability of each test to predict protective CMV-specific T-cell responses. Two hundred twenty-one Quantiferon-CMV and ELISPOT tests were conducted on 120 adult kidney transplant… CONTINUE READING