Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

@article{Nelson2004ComparisonOC,
  title={Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.},
  author={David R. Nelson and Darryl C. Zeldin and Susan M. G. Hoffman and Lois J. Maltais and Hester M. Wain and Daniel W. Nebert},
  journal={Pharmacogenetics},
  year={2004},
  volume={14 1},
  pages={
          1-18
        }
}
OBJECTIVES Completion of both the mouse and human genome sequences in the private and public sectors has prompted comparison between the two species at multiple levels. This review summarizes the cytochrome P450 (CYP) gene superfamily. For the first time, we have the ability to compare complete sets of CYP genes from two mammals. Use of the mouse as a model mammal, and as a surrogate for human biology, assumes reasonable similarity between the two. It is therefore of interest to catalog the… 

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