Comparison of computational methods for the identification of cell cycle-regulated genes

@article{Lichtenberg2005ComparisonOC,
  title={Comparison of computational methods for the identification of cell cycle-regulated genes},
  author={Ulrik de Lichtenberg and Lars Juhl Jensen and Anders Fausb{\o}ll and Thomas Sk{\o}t Jensen and Peer Bork and S{\o}ren Brunak},
  journal={Bioinformatics},
  year={2005},
  volume={21 7},
  pages={
          1164-71
        }
}
MOTIVATION DNA microarrays have been used extensively to study the cell cycle transcription programme in a number of model organisms. The Saccharomyces cerevisiae data in particular have been subjected to a wide range of bioinformatics analysis methods, aimed at identifying the correct and complete set of periodically expressed genes. RESULTS Here, we provide the first thorough benchmark of such methods, surprisingly revealing that most new and more mathematically advanced methods actually… CONTINUE READING

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