Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels.

@article{Prudom2010ComparisonOC,
  title={Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels.},
  author={Catherine E Prudom and Jianhua Liu and James M Patrie and Bruce D Gaylinn and Karen E Foster-Schubert and David Cummings and Michael O. Thorner and H. Mario Geysen},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2010},
  volume={95 5},
  pages={2351-8}
}
CONTEXT Ghrelin, an endogenous ligand for the GH secretagogue receptor, is an orexigenic peptide hormone produced primarily by the stomach. Recent studies suggest significant differences in the specificity of currently available ghrelin assays. OBJECTIVE The aim of the study was to compare four ghrelin assays (two commercially available and two developed by our group) of differing specificity, each used on the same set of more than 800 plasma samples from a human study. DESIGN Thirteen… CONTINUE READING
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