Comparison of colorectal cancer in differentially established liver metastasis models.

@article{Lee2014ComparisonOC,
  title={Comparison of colorectal cancer in differentially established liver metastasis models.},
  author={Woo Yong Lee and Hye Kyung Hong and Soo Kyung Ham and Chang In Kim and Yong B. Cho},
  journal={Anticancer research},
  year={2014},
  volume={34 7},
  pages={3321-8}
}
BACKGROUND Metastasis is one of the main reasons for colorectal cancer (CRC)-related deaths due to the lack of effective therapeutics mainly for liver metastasis. In the present study, we established an orthotopic colorectal cancer mouse model using different transplantation protocols to determine the optimal conditions for CRC liver metastasis. MATERIALS AND METHODS Luciferin-expressing HCT116 cells were used to induce liver metastasis models of colorectal cancer following both intra-splenic… CONTINUE READING

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