Comparison of clonidine and dexmedetomidine for short-term sedation of intensive care unit patients

@inproceedings{Srivastava2014ComparisonOC,
  title={Comparison of clonidine and dexmedetomidine for short-term sedation of intensive care unit patients},
  author={Uma Shankar Srivastava and Mita Eunice Sarkar and A. Arun Kumar and Amrita Gupta and Archana Agarwal and Tapas Kumar Singh and Vivek Badada and Yogita Dwivedi},
  booktitle={Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine},
  year={2014}
}
BACKGROUND AND OBJECTIVES Patients on mechanical ventilation in intensive care unit (ICU) are often uncomfortable because of anxiety, pain, and endotracheal intubation; therefore, require sedation. Alpha-2 agonists are known to produce sedation. We compared clonidine and dexmedetomidine as sole agents for sedation. STUDY DESIGN Prospective, randomized, controlled open-label study. MATERIALS AND METHODS A total of 70 patients requiring a minimum of 12 h of mechanical ventilation with… CONTINUE READING
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