Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction, achievement of pregnancy, and live birth in Asian women with polycystic ovary syndrome: a randomized controlled trial.

@article{Zain2009ComparisonOC,
  title={Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction, achievement of pregnancy, and live birth in Asian women with polycystic ovary syndrome: a randomized controlled trial.},
  author={Murizah Mohd Zain and Ridzuan Jamaluddin and Adibah Ibrahim and Robert J. Norman},
  journal={Fertility and sterility},
  year={2009},
  volume={91 2},
  pages={
          514-21
        }
}
OBJECTIVE To determine the first-line medication to be used in anovulatory patients with polycystic ovary syndrome (PCOS) for ovulation induction and pregnancy achievement. DESIGN Randomized controlled trial. SETTING Infertility unit of a public hospital. PATIENT(S) One hundred fifteen newly diagnosed patients with PCOS based on ESHRE/ASRM criteria. INTERVENTION(S) These patients were assigned to three groups: group 1 (38 patients) received 500 mg of metformin three times a day; group 2… CONTINUE READING
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