Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction and achievement of pregnancy in 154 women with polycystic ovary syndrome.

@article{Neveu2007ComparisonOC,
  title={Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction and achievement of pregnancy in 154 women with polycystic ovary syndrome.},
  author={Nathalie Neveu and Louis Granger and Pierre St-Michel and H{\'e}l{\`e}ne B. Lavoie},
  journal={Fertility and sterility},
  year={2007},
  volume={87 1},
  pages={113-20}
}
OBJECTIVE To determine which first-line medication is more effective in polycystic ovary syndrome (PCOS) patients for ovulation induction and pregnancy achievement and to verify whether any patient characteristic is associated with a better response to therapy. DESIGN Observational comparative study. SETTING Fertility clinic. PATIENT(S) One hundred fifty-four infertile women with oligomenorrhea and hyperandrogenism. INTERVENTION(S) Group 1 (56 patients) received clomiphene citrate (CC… CONTINUE READING

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The use of metformin in the management of polycystic ovary syndrome and associated anovulatory infertility: the current evidence.

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