Comparison of clinical cure rates in adults with ventilator-associated pneumonia treated with intravenous ceftazidime administered by continuous or intermittent infusion: a retrospective, nonrandomized, open-label, historical chart review.

@article{Lorente2007ComparisonOC,
  title={Comparison of clinical cure rates in adults with ventilator-associated pneumonia treated with intravenous ceftazidime administered by continuous or intermittent infusion: a retrospective, nonrandomized, open-label, historical chart review.},
  author={Leonardo Lorente and Alejandro Mart{\'i}nez Jim{\'e}nez and Salom{\'e} Palmero and Juan Jos{\'e} Jim{\'e}nez and Jos{\'e} Lu{\'i}s Iribarren and Melit{\'o}n Santana and Maria del Mar Badia Mart{\'i}n and Mar{\'i}a Luisa Mora},
  journal={Clinical therapeutics},
  year={2007},
  volume={29 11},
  pages={2433-9}
}
BACKGROUND Beta-lactam antibiotics are reported to exhibit time-dependent bactericidal activity. However, there are limited data on the clinical efficacy of ceftazidime administered by continuous infusion. OBJECTIVE The objective of this study was to compare the clinical efficacy of ceftazidime administered by continuous infusion and by intermittent infusion in the treatment of ventilator-associated pneumonia (VAP) caused by gram-negative bacteria. METHODS This was a retrospective chart… CONTINUE READING

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