Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples.

@article{Plassman2006ComparisonOC,
  title={Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples.},
  author={Brenda L. Plassman and Ara S. Khachaturian and Jeannette J. Townsend and Melvyn J. Ball and David C. Steffens and Carol E Leslie and JoAnn T. Tschanz and Maria C. Norton and James R Burke and Kathleen Welsh-Bohmer and Christine M. Hulette and Randal R Nixon and Mary Tyrey and John C. S. Breitner},
  journal={Alzheimer's & dementia : the journal of the Alzheimer's Association},
  year={2006},
  volume={2 1},
  pages={2-11}
}
BACKGROUND Studies of dementia in populations avoid many of the selection biases in clinical samples but require special evaluation and diagnostic methods to obtain high participation rates. To address this issue, we developed a unique in-home dementia assessment. We assessed validity of these assessments using neuropathologic confirmation of the clinical diagnosis in 3 epidemiologic samples. METHODS Subjects were 175 participants in 3 ongoing studies of dementia. Two were population based… CONTINUE READING