Comparison of chromosome analysis and BCL-1 rearrangement in a series of patients with multiple myeloma.

@article{Fiedler1992ComparisonOC,
  title={Comparison of chromosome analysis and BCL-1 rearrangement in a series of patients with multiple myeloma.},
  author={Walter Fiedler and H. J. Weh and Dieter Kurt Hossfeld},
  journal={British journal of haematology},
  year={1992},
  volume={81 1},
  pages={58-61}
}
Translocation (11;14)(q13;q32) is a recurring chromosome abnormality which is found non-randomly in non-Hodgkin's lymphoma, especially of follicular type, as well as in B-cell chronic lymphocytic leukaemia, Waldenström's macroglobulinaemia and multiple myeloma. To define further the prevalence of this abnormality in multiple myeloma, we studied a series of 17 patients with this disease with concomitant chromosome analysis and Southern blotting, using a probe specific for the major translocation… CONTINUE READING
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