Comparison of charge state determination methods for high resolution mass spectra

@article{Kaur2006ComparisonOC,
  title={Comparison of charge state determination methods for high resolution mass spectra},
  author={Parminder Kaur and Peter B. O'Connor},
  journal={2006 IEEE International Conference on Granular Computing},
  year={2006},
  pages={550-553}
}
Since mass spectrometers measure mass/charge ratio rather than mass, determination of charge state is essential in order to determine mass. Charge state determination requires methods to accurately estimate the m/z difference between adjacent isotopic peaks. This is particularly difficult under conditions of low SNR and when isotopic clusters are poorly resolved. A new method for charge state determination using the Matched Filter approach that has been recently developed is presented and… CONTINUE READING

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