Comparison of ceftibuten once daily and amoxicillin-clavulanate three times daily in the treatment of acute exacerbations of chronic bronchitis.

@article{McAdoo1998ComparisonOC,
  title={Comparison of ceftibuten once daily and amoxicillin-clavulanate three times daily in the treatment of acute exacerbations of chronic bronchitis.},
  author={Michael A McAdoo and Kathryn Rice and George R. Gordon and Steven A. Sahn},
  journal={Clinical therapeutics},
  year={1998},
  volume={20 1},
  pages={88-100}
}
In medical practice, antibiotics are generally given empirically for the treatment of acute exacerbations of chronic bronchitis (AECB). To be effective, antibiotic therapy should be broad in spectrum, and it should also cover the common beta-lactamase-producing pathogens. In this multicenter, randomized, investigator-masked study, 469 patients with AECB were randomized (in a ratio of 2:1) to receive 400-mg oral ceftibuten capsules once daily or 500-mg amoxicillin-clavulanate tablets three times… CONTINUE READING

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BronchitisMay be treated byceftibuten
Both treatments improved the signs and symptoms of bronchitis , and overall clinical success rates were equivalent for patients treated with ceftibuten ( 211 of 252 [ 84% ] ) and amoxicillin - clavulanate ( 93 of 117 [ 79% ] ) ( 95% confidence interval [ CI ] , -4.5% to 13.6% ) .
Comparison of ceftibuten once daily and amoxicillin - clavulanate three times daily in the treatment of acute exacerbations of chronic bronchitis .
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