Comparison of cardiac electrophysiologic effects of experimental hypothyroidism and chronic oral amiodarone administration in dogs.

@article{Liu1994ComparisonOC,
  title={Comparison of cardiac electrophysiologic effects of experimental hypothyroidism and chronic oral amiodarone administration in dogs.},
  author={Peter M. Liu and Xiao-Wei Zhang and Wei Wu and Jiu-jun Li and Yan-hong Tang},
  journal={Chinese medical journal},
  year={1994},
  volume={107 5},
  pages={375-9}
}
A comparative study on ventricular electrophysiologic effects of experimental hypothyroidism and chronic oral amiodarone administration was made in canine models, with the application of electrical stimulation and monophasic action potential recording. The results showed similar effects possessed by hypothyroidism and amiodarone, which included prolongations in ventricular repolarization and refractoriness, an increase in ventricular fibrillation threshold, and a decrease in the incidence of… CONTINUE READING

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