Comparison of budesonide and 5-aminosalicylic acid enemas in active distal ulcerative colitis.

@article{Lmann1995ComparisonOB,
  title={Comparison of budesonide and 5-aminosalicylic acid enemas in active distal ulcerative colitis.},
  author={Marc L{\'e}mann and Annie Galian and P. R. Rutgeerts and R Van Heuverzwijn and Antoine Cortot and J M Viteau and Ann Elewaut and Jacques Belaiche and Eric Froguel and Robert Modigliani},
  journal={Alimentary pharmacology & therapeutics},
  year={1995},
  volume={9 5},
  pages={557-62}
}
BACKGROUND Budesonide is a new corticosteroid with high topical anti-inflammatory activity but little systemic effect. The aim of the present study was to compare the efficacy and safety of budesonide enema (2 mg/100 mL) and 5-ASA enema (mesalazine 1 g/100 mL) given for 4 weeks in the treatment of active distal ulcerative colitis and proctitis. METHODS Ninety-seven patients were studied in a multicentre single-blind randomized group-comparative trial. The primary efficacy variables were… CONTINUE READING

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