Comparison of bronchodilating and antiinflammatory activities of oral formoterol and its (R,R)-enantiomers.

@article{Xie2003ComparisonOB,
  title={Comparison of bronchodilating and antiinflammatory activities of oral formoterol and its (R,R)-enantiomers.},
  author={Qiang-min Xie and Ji-qiang Chen and Wen-hui Shen and Qiu-huo Yang and Ru-lian Bian},
  journal={Acta pharmacologica Sinica},
  year={2003},
  volume={24 3},
  pages={277-82}
}
AIM To compare the bronchodilating and antiinflammatory effects of oral racemic formoterol (rac-FMT) and (R,R)-formoterol (R,R-FMT). METHODS The changes of lung resistance (RL), dynamic lung compliance (Cdyn), and the accumulation of inflammatory cells in bronchoalveolar lavage fluids (BALF) induced by ovalbumin aerosol in sensitized guinea pigs and mice were investigated in vivo. RESULTS Mean value increase of RL and mean value reduction of Cdyn from 1 to 30 min after antigen challenge… CONTINUE READING

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