Comparison of brain urocortin-3 and corticotrophin-releasing factor for physiological responses in chicks

@article{Ogino2014ComparisonOB,
  title={Comparison of brain urocortin-3 and corticotrophin-releasing factor for physiological responses in chicks},
  author={Madoka Ogino and Aki Okumura and Md. Sakirul Islam Khan and M A Cline and Tetsuya Tachibana},
  journal={Physiology & Behavior},
  year={2014},
  volume={125},
  pages={57-61}
}
Corticotrophin-releasing hormone (CRH) plays an important role in response to stress, and exerts a physiological effect via its receptor, CRH receptor type-1 (CRH-R1) and CRH receptor type-2 (CRH-R2) with high affinity to CRH-R1 in mammals. Urocortin-3 (UCN-3), a CRH family peptide, is an endogenous ligand for CRH-R2 in mammals. The physiological roles of UCN-3 and CRH-R2 have been investigated in mammals, although their roles still need to be clarified in chicks (Gallus gallus). Few studies… CONTINUE READING
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