Comparison of bovine and porcine heparin in heparin antibody formation after cardiac surgery.

@article{Francis2003ComparisonOB,
  title={Comparison of bovine and porcine heparin in heparin antibody formation after cardiac surgery.},
  author={John L. Francis and George J Palmer and Rebecca L Moroose and Alane Drexler},
  journal={The Annals of thoracic surgery},
  year={2003},
  volume={75 1},
  pages={17-22}
}
BACKGROUND Heparin-induced thrombocytopenia (HIT) is a potentially devastating complication of heparin therapy. The incidence of clinical HIT after cardiovascular surgery is less than 2%, although asymptomatic antibodies to heparin-platelet factor 4 (PF4) occur more frequently. Bovine heparin is thought to cause more HIT than porcine heparin, although this has never been established for heparin use during coronary artery bypass grafting. We therefore undertook a randomized, prospective study of… CONTINUE READING

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