Comparison of blinding effectiveness between sham tDCS and placebo sertraline in a 6-week major depression randomized clinical trial.

@article{Brunoni2014ComparisonOB,
  title={Comparison of blinding effectiveness between sham tDCS and placebo sertraline in a 6-week major depression randomized clinical trial.},
  author={Andr{\'e} Russowsky Brunoni and Pedro Schestatsky and Paulo Andrade Lotufo and Isabela Judith Martins Bense{\~n}or and Felipe Fregni},
  journal={Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology},
  year={2014},
  volume={125 2},
  pages={298-305}
}
OBJECTIVE To compare blinding integrity and associated factors for transcranial direct current stimulation (tDCS) vs. placebo-pill, the gold standard blinding method. METHODS Parallel trial. Depressed participants were randomized to verum/placebo sertraline and active/sham tDCS (2mA, 30-min 10-daily sessions and two additional, fortnight sessions) over 6weeks. Blinding was assessed in completers (n=102) and in a random subgroup (n=35) of raters and participants, in which we also inquired to… CONTINUE READING
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