Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing.

@article{Isaksson2006ComparisonOB,
  title={Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing.},
  author={Hanna Isaksson and Wouter Wilson and Corrinus C. van Donkelaar and Rik Huiskes and Keita Ito},
  journal={Journal of biomechanics},
  year={2006},
  volume={39 8},
  pages={1507-16}
}
Most long-bone fractures heal through indirect or secondary fracture healing, a complex process in which endochondral ossification is an essential part and bone is regenerated by tissue differentiation. This process is sensitive to the mechanical environment, and several authors have proposed mechano-regulation algorithms to describe it using strain, pore pressure and/or interstitial fluid velocity as biofeedback variables. The aim of this study was to compare various mechano-regulation… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

Implant-bone interface healing and adaptation in resurfacing hip replacement.

Computer methods in biomechanics and biomedical engineering • 2012
View 5 Excerpts
Highly Influenced

Finite Element Method (FEM), Mechanobiology and Biomimetic Scaffolds in Bone Tissue Engineering

International journal of biological sciences • 2011
View 3 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 35 references

The cell and molecular biology of fracture healing.

Clinical orthopaedics and related research • 1998
View 3 Excerpts
Highly Influenced

Role of mechanical loading in the progressive ossification of a fracture callus.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society • 1989
View 7 Excerpts
Highly Influenced

Correlations between mechanical stress history and tissue differentiation in initial fracture healing.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society • 1988
View 8 Excerpts
Highly Influenced

Mechanobiology of skeletal regeneration.

Clinical orthopaedics and related research • 1998
View 12 Excerpts
Highly Influenced

Biophysical stimuli on cells during tissue differentiation at implant interfaces

P. J. Prendergast, R. Huiskes, K. Soballe
ESB Research Award • 1997
View 5 Excerpts
Highly Influenced

Beneficial effects of moderate, early loading and adverse effects of delayed or excessive loading on bone healing

A. Bailòn-Plaza, M. C. van der Meulen
Journal of Biomechanics • 2003

Similar Papers

Loading similar papers…