Comparison of biochemical aromatase activity with aromatase immunhistochemistry in human breast carcinomas

@article{Shenton1998ComparisonOB,
  title={Comparison of biochemical aromatase activity with aromatase immunhistochemistry in human breast carcinomas},
  author={Karyn Shenton and Mitch Dowsett and Qing Lu and A. Brodie and Hironobu Sasano and N. Sacks and Martin G. Rowlands},
  journal={Breast Cancer Research and Treatment},
  year={1998},
  volume={49},
  pages={S101-S107}
}
The role of intratumoural aromatase in human breast cancer growth remains controversial. At the same time as the use of aromatase inhibitors in the clinical setting continues to increase, so does the need for a tool to predict the likely response to this treatment. Intratumoural aromatase is a candidate predictive marker. The presently accepted 'gold standard' methods of assessment of aromatase activity are biochemical assays. However, these are time-consuming and require relatively large… CONTINUE READING

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