Comparison of assays for growth hormone using monoclonal or polyclonal antibodies for diagnosis of growth disorders.

@article{Levin1987ComparisonOA,
  title={Comparison of assays for growth hormone using monoclonal or polyclonal antibodies for diagnosis of growth disorders.},
  author={Philip A Levin and Stuart Chalew and Lucile Martin and Avinoam A. Kowarski},
  journal={The Journal of laboratory and clinical medicine},
  year={1987},
  volume={109 1},
  pages={85-8}
}
Current diagnostic standards for growth hormone deficiency were derived from measurement of growth hormone using polyclonal antibody assays. Recently, however, immunoassays using monoclonal antibodies to growth hormone have been commercially introduced. This study compares growth hormone levels obtained with two new monoclonal assays with levels obtained with a standard polyclonal assay. In 20 patients, the polyclonal assay (National Pituitary Agency) measured a mean growth hormone… CONTINUE READING

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