Comparison of artesunate and quinine in the treatment of Sudanese children with severe Plasmodium falciparum malaria.

@article{Eltahir2010ComparisonOA,
  title={Comparison of artesunate and quinine in the treatment of Sudanese children with severe Plasmodium falciparum malaria.},
  author={Hatim G Eltahir and Abubaker A Omer and Ayoub A Mohamed and Ishag Adam},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={2010},
  volume={104 10},
  pages={684-6}
}
Sixty-six children presenting to Singa hospital, Sudan with different manifestations of severe Plasmodium falciparum malaria were randomly divided into two well-matched groups (33 in each arm) to receive either intravenous artesunate 2·4 mg/kg at 0, 12, and 24 hours, then daily, or intravenous quinine 20mg/kg initially then 10mg/kg three times a day. There was no significant difference in the fever, parasite clearance, and coma resolution times. Three patients died, one in the artesunate and… CONTINUE READING
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