Comparison of apheresis and other methods for separation and purification of hemopoietic stem cells: initial experience with a blood buffy coat model for the use of autologous bone marrow transplantation.

@article{Arnaud1984ComparisonOA,
  title={Comparison of apheresis and other methods for separation and purification of hemopoietic stem cells: initial experience with a blood buffy coat model for the use of autologous bone marrow transplantation.},
  author={Françoise Arnaud and G Riemersma and Cees Th Smit Sibinga and Prokash Das},
  journal={The International journal of artificial organs},
  year={1984},
  volume={7 3},
  pages={127-32}
}
With an increasing number of bone marrow transplantations (BMT) being contemplated in leukemia and cancer patients, it is prudent for blood banks to develop a suitable program within their resources for harvesting, purifying and freezing bone marrow stem cells. In order to do this, initially a prototype has been developed involving buffy coat model (BC) using normal donor blood. Centrifugation, sedimentation and machine apheresis methods were separately evaluated leading to a combined and… CONTINUE READING