Comparison of antiplatelet effect and tolerability of clopidogrel resinate with clopidogrel bisulfate in patients with coronary heart disease (CHD) or CHD-equivalent risks: a phase IV, prospective, double-dummy, parallel-group, 4-week noninferiority trial.

Abstract

BACKGROUND Clopidogrel resinate is a resinate complex of (+)-clopidogrel optical isomer, wherein the (+)-clopidogrel isomer binds to a water-soluble cation exchange resin via sulfonic acid groups. It was approved by the Korean Food and Drug Administration on the basis of a Phase I study that demonstrated the bioequivalence of clopidogrel resinate and… (More)
DOI: 10.1016/j.clinthera.2011.07.001

Topics

Cite this paper

@article{Suh2011ComparisonOA, title={Comparison of antiplatelet effect and tolerability of clopidogrel resinate with clopidogrel bisulfate in patients with coronary heart disease (CHD) or CHD-equivalent risks: a phase IV, prospective, double-dummy, parallel-group, 4-week noninferiority trial.}, author={Jung Won Suh and Ki-Bae Seung and Chung-Hwan Gwak and Kwon-Sam Kim and Soon-Jun Hong and Tae-Ho Park and Sang-Yong Kim and Young-Jin Choi and Seung-Jea Joo and Seung Jea Tahk and Hyo Soo Kim}, journal={Clinical therapeutics}, year={2011}, volume={33 8}, pages={1057-68} }