Comparison of an anti-rabies human monoclonal antibody combination with human polyclonal anti-rabies immune globulin.

@article{Goudsmit2006ComparisonOA,
  title={Comparison of an anti-rabies human monoclonal antibody combination with human polyclonal anti-rabies immune globulin.},
  author={Jaap Goudsmit and Wilfred E. Marissen and William C. Weldon and Michael Niezgoda and Cathleen Alma Hanlon and Amy B. Rice and John de Kruif and Bernhard Dietzschold and Alexander B H Bakker and Charles E. Rupprecht},
  journal={The Journal of infectious diseases},
  year={2006},
  volume={193 6},
  pages={
          796-801
        }
}
The World Health Organization estimates human mortality from endemic canine rabies to be 55,000 deaths/year. Limited supply hampers the accessibility of appropriate lifesaving treatment, particularly in areas where rabies is endemic. Anti-rabies antibodies are key to protection against lethal rabies. Currently, only human and equine polyclonal anti-rabies immune globulin (HRIG and ERIG) is available. Replacement of HRIG and ERIG with a safer and more widely available product is recommended. We… CONTINUE READING

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