Comparison of an anti-rabies human monoclonal antibody combination with human polyclonal anti-rabies immune globulin.

@article{Goudsmit2006ComparisonOA,
  title={Comparison of an anti-rabies human monoclonal antibody combination with human polyclonal anti-rabies immune globulin.},
  author={Jaap Goudsmit and Wilfred E. Marissen and William C. Weldon and Michael Niezgoda and Cathleen Alma Hanlon and Amy B. Rice and John de Kruif and Bernhard Dietzschold and Alexander Berthold Hendrik Bakker and Charles E. Rupprecht},
  journal={The Journal of infectious diseases},
  year={2006},
  volume={193 6},
  pages={
          796-801
        }
}
The World Health Organization estimates human mortality from endemic canine rabies to be 55,000 deaths/year. Limited supply hampers the accessibility of appropriate lifesaving treatment, particularly in areas where rabies is endemic. Anti-rabies antibodies are key to protection against lethal rabies. Currently, only human and equine polyclonal anti-rabies immune globulin (HRIG and ERIG) is available. Replacement of HRIG and ERIG with a safer and more widely available product is recommended. We… CONTINUE READING

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