Comparison of agents that affect aldosterone action.

Abstract

The first aldosterone blocker, spironolactone, initially was used as a diuretic but was accompanied by a significant amount of side effects that necessitated the withdrawal of the drug in a relevant number of patients. The discovery of the many receptor-mediated actions of aldosterone in several different organs greatly contributed to expand the indications… (More)
DOI: 10.1016/j.semnephrol.2014.04.005

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.