Comparison of a second-generation combination chemotherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced diffuse non-Hodgkin's lymphoma.

@article{Gordon1992ComparisonOA,
  title={Comparison of a second-generation combination chemotherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced diffuse non-Hodgkin's lymphoma.},
  author={Leo I Gordon and David Harrington and Jorn Andersen and Jane Colgan and John Glick and Richard A Neiman and Rebecca L. Mann and Gary Resnick and Maurice Barcos and Arlan J. Gottlieb},
  journal={The New England journal of medicine},
  year={1992},
  volume={327 19},
  pages={1342-9}
}
BACKGROUND In 1984, the Eastern Cooperative Oncology Group began a randomized controlled clinical trial of patients with advanced (stage III or IV) diffuse mixed or diffuse large-cell lymphoma to determine whether complete-remission rates, survival, and toxicity differed when patients were treated with a chemotherapeutic regimen containing cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), as compared with a regimen containing bleomycin, doxorubicin, cyclophosphamide… CONTINUE READING
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