Comparison of a multiplex, bead-based fluorescent assay and immunofluorescence methods for the detection of ANA and ANCA autoantibodies in human serum.

@article{Nifli2006ComparisonOA,
  title={Comparison of a multiplex, bead-based fluorescent assay and immunofluorescence methods for the detection of ANA and ANCA autoantibodies in human serum.},
  author={Artemissia-Phoebe Nifli and George Notas and M Mamoulaki and Maria Niniraki and Vaso Ampartzaki and Panayiotis A. Theodoropoulos and Mark J Kopnitsky and Elias Castanas},
  journal={Journal of immunological methods},
  year={2006},
  volume={311 1-2},
  pages={
          189-97
        }
}
  • Artemissia-Phoebe Nifli, George Notas, +5 authors Elias Castanas
  • Published in
    Journal of immunological…
    2006
  • Medicine
  • Detection of antinuclear (ANA) and antineutrophil cytoplasmic (ANCA) antibodies is extensively used for establishing a diagnosis in patients with clinical features suggestive of autoimmune disorders. The most common methods for the identification of positive patients' sera for ANA or ANCA are indirect immunofluorescence (IIF) and ELISA-based procedures. Considerable effort has been made in developing simpler automated assays for routine laboratory use. Recently a commercially available… CONTINUE READING

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